منابع مشابه
Blue Lunula Related with Hydroxyurea
100 Hydroxyurea, which is an inhibitor of ribonucleoside reductase and is used as a systemic antitumor agent, is frequently used for the treatment of myeloproliferative and hematologic diseases. While the most common side effect is myelosuppression, gastrointestinal symptoms such as nausea, vomiting, stomatitis, and anorexia and rash, skin ulcers, hyperpigmentation in nails, and dermatologic to...
متن کاملHydroxyurea Induced Longitudinal Melanonychia: A Picture Presentation
This is a picture presentation of myeloproliferative disorder developing to longitudinal melanonychia as a side effect of hydroxyurea. Keywords: Melanonychia, hydroxyurea, side effect.
متن کاملHydroxyurea Induced Perimalleolar Ulcers
Hydroxyurea (HU) is an antineoplastic drug commonly used to treat chronic myeloproliferative disorders. Common dermatological side effects include hyperpigmentation, scaling, erythema, alopecia, desquamation of face and hands. Leg ulceration following HU therapy is less common and very few cases have been reported so far. Objective of this paper is to increase the awareness of hydroxyurea induc...
متن کاملA Hydroxyurea-induced Leg Ulcer.
Hydroxyurea is a cytostatic agent that has recently become the drug of choice in the treatment of various myeloproliferative diseases. The cutaneous side effects of hydroxyurea include xerosis, hyperpigmentation, nail discoloration, and scaling. Leg ulcers have only rarely been reported in association with hydroxyurea treatment. A 75-year-old woman presented with leg ulcers, nail discoloration,...
متن کاملBlack lunula caused by Tegafur.
Sir, Tegafur, a fluorinated pyrimidine analogue of 5Fluorouracil (5-FU), is metabolized in vivo with biotransformation to 5-FU (1). It is effective in the treatment of gastrointestinal carcinoma, with the advantages of low myelosuppression and lack of immunosuppression. The cutaneous adverse effects of Tegafur include stomatitis, dry skin, disseminated rash, alopecia, photosensitivity, palmopla...
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ژورنال
عنوان ژورنال: Journal of Dermatology and Dermatologic Surgery
سال: 2021
ISSN: 2352-2410
DOI: 10.4103/jdds.jdds_14_20